Arthritis and male fertility, what is your relationship?

This pathology is related to male infertility, erectile dysfunction and insufficient testosterone production.

Varieties of inflammatory proteins that interfere with the associated immune system and inflammatory arthritis, exhibiting a papillary cortex in the regulation of sperm production. Photo: Shutterstock.

Rheumatoid arthritis or one of the other types of inflammatory arthritis, diagnosed before or after high levels of reproductive activity, can slow down the fertility of men, by conducting an online public investigationAnnals of the Rheumatic Diseases’.

Inflammatory arthritis is associated with the paternity of meningitis, a degree of infertility, the involuntary auditory deedor fertility problems, such as semen calorific value, are the results of this study.

This pathology, which includes rheumatoid arthritis, psoriatic arthritis, juvenile idiopathic arthritis and ankylosing spondylitis, is related to masculine infertility, erectile dysfunction and insufficient testosterone production y / o sperm (hypogonadism). Pero el impact of inflammatory arthritis in the capacity of the men to make sure they are in a disconnected medium.

To explore this quest, investigators, directed by Luis Fernando Perez-García, rheumatologist at Erasmus Medical Center in Pa Bajses Bajos, compare fertility bowl, or number of shadows per hombre, among men diagnosed with inflammatory arthritis as a function of their age at the time of diagnosis; 30 years or less; between 31 and 40 years (considering the maximum reproductive age); and 41 years or more.

The participants received extra 8 different hospitals from Pa Bajes Bajos between September 2019 and January 2021. Unos 628, majors of 40 years and which indicates that the family’s size is complete, rel questionnaire about medical problems and fertility that has been shown to be antispasmodic for diagnosing inflammatory arthritis.

The investigators are also comparable the total number of embassies vinculados con cada hombre, el tamaño deseado de la familia, la proportion of men without hair y los results of medical evaluations for fertility problems.

Adjust the potentially influential factors, such as current age, educational level, antecedents of cardiovascular impairment and parietal infertility, how to diagnose any type of inflammatory arthritis over the last 30 years or so. the men of the other edos groups.

These men only have a media of 1.32 shadows, front to 1.56 of those diagnosed between 31 and 40 years old, and 1.88 of those diagnosed when they are only 41 years old or older.

Men diagnosed before or after only 30 years of age with a small amount of tuberculosis (1.45) who are diagnosed between 31 and 40 years (1.73) or major (1.98). In the Bajos Countries, between 1 of 5 and 1 of 4 people there are no shadows. Among the participants, 143 (more than 22%) did not have shadows, of which approximately three (99; 69%) did not have voluntary shadows.

One more item, the percentage of men without shadows is significantly higher among those diagnosed before 30 years (45; 34%), among those diagnosed between 31 and 40 years (39; 27%) and those diagnosed with 40 years (59; 17%).

Además, la proportion of men without hair of the involuntary form fue significantly different between the 3 groups: respectively, 16 (12%); 15 (10%); y 13 (4%). The volume of voluntary shadows varied by 29% (25%); 24 (18%); y 46 (15%).

However, among those who do not only have voluntary shadows, the affirmation ‘My nurse reduced my tenor’s wish’, qualifies more alto than men diagnosed as more young than those who qualify from other groups of age.

Además, a significantly higher number of men diagnosed before or over 30 years (17%) and between 31 and 40 years (10%) declares insatisfaction with the final number of shadows that men diagnosed when they are major (5.5 %). Altering a third of these men to be seen as the main reason for having their own diagnostic and / or medical treatment associated with mismo.

In comparison with the group of mayor, a significant number of mayors who have been diagnosed with anthrax or those with high levels of fertility declare that they have been evaluated medically for fertility problems, resulting in a small amount of semen.

Due to the number of tenths of a few small in the most frequently diagnosed and endangered species, there are no significant differences between the 3 groups, in general, and similar to the number of communications per group by the total population of the region. .

However, investigators say that “the difference between the number of lost shadows and the final one is significantly greater in the first diagnosed and endangered species, which indicates that the most fertile bowls are mainly affected by the reduced fertility potential and not for a lesser degree of desperation “.

To study an observation study, as it were, could not establish the cause, not the obstruction, but all the plausible biological explanations before the associations were found, the investigators explained.

Variants of inflammatory proteins that interfere with the associated immune system and inflammatory arthritis, such as tumor necrosis factor (TNF), exhibit a papillary cortex in the regulation of testicular stabilization and sperm production.

Pharmacies used to treat arthritis are treated with a paper towel, they suggest. Secondary effects such as hypogonadism and sperm maladaptation are associated with frequent use of immunosuppressive agents.

It is calculated between men and women that involuntarily increase infertility clinics, 1 of 4 drugs that affect sexual function, 1 of 10 drugs associated with infertility.

Assimilation, various psychosocial, associative and diagnostic factors, can be contributed to by the small amount of fertility, suggest the investigators.

“Debid on problems or concerns associated with diagnosis and treatment, and based on medical advice (or in the case of inflammation), men with inflammatory arthritis and their pairs deciding to voluntarily return to the shadows padres –explican–. These are psychosocial factors of special importation for men diagnosed at the peak of reproductive age “.

Where consulted here.